MMP1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77264A
Western Blot analysis of PC3 cell and Mouse muscle tissue, A375 cell using MMP1 Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human liver cancer using MMP1 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer using MMP1 Polyclonal Antibody at dilution of 1:60
Product Name
MMP1 Polyclonal Antibody
Catalog Number
RD77264A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human MMP1
Swissprot
P03956
Synonyms
27 kDa interstitial collagenaseCLGCLGNcollagenasefibroblastcollagenaseinterstitialFibroblast collagenaseInterstitial collagenaseMatrix metallopeptidase 1 (interstitial collagenase)Matrix metalloprotease 1Matrix Metalloproteinase 1Matrix metall
Calculated MW
54 kDa
Gene Accession
BC013875
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas