MMP2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70270A
Immunohistochemistry analysis of paraffin-embedded human colon cancer using MMP2 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded rat colon using MMP2 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded mouse uterus using MMP2 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry analysis of paraffin-embedded Human Spleen using MMP2 Polyclonal Antibody.
Product Name
MMP2 Polyclonal Antibody
Catalog Number
RD70270A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
MMP2,also named as CLG4A,Gelatinase Am,TBE-1 and PEX,belongs to the peptidase M10A family. It is ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature,angiogenesis,tissue repair,tumor invasion,inflammation,and atherosclerotic plaque rupture. MMP2 contributes to myocardial oxidative stress by regulating the activity of GSK3beta. It cleaves GSK3beta in vitro. MMP2 can be cleaved into PEX chain(~60kd).Western blot analysis showed that the 72 kDa and 62 kDa proteinase activities were pro-MMP2 and the active enzyme,respectively.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse MMP2
Swissprot
P08253,P33436,P33434
Synonyms
72 kDa gelatinase72kD type IV collagenaseCLG 4CLG 4ACLG4CLG4ACollagenase Type 4 alphaCollagenase type IV AGelatinase AGelatinase alphaGelatinase neutrophilMatrix metallopeptidase 2 gelatinase A 72kDa gelatinase 72kDa type IV collagenaseMatrix
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:500-1:2000
Concentration
0.82 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas