The CW domain is a structural module found in many vertebrate, parasitic and plant proteins. It consists of a mononuclear four-cysteine zinc-finger domain that plays a role in DNA binding, chromatin methylation and early embryonic development. ZCWCC1 (zinc finger CW-type coiled-coil domain protein 1), also known as MORC2 (MORC family CW-type zinc finger protein 2) or ZCW3, is a 1,032 amino acid protein that contains one CW-type zinc finger domain. ZCWCC1 is located on chromosome 22 and is ubiquitously expressed with highest expression in pancreas, smooth muscle and testis. Expression of ZCWCC1 is upregulated in hypoxia, a pathological condition characterized by an inadequate supply of oxygen in the blood.
Immunogen Information
Immunogen
Fusion protein of human MORC2
Swissprot
Q9Y6X9
Synonyms
AC004542.C22.1.CW type with coiled coil domain 1KIAA0852MORC family CW type zinc finger 2MORC family CW-type zinc finger protein 2MORC2MORC2ZCW3ZCWCC1Zinc fingerZinc finger CW type coiled coil domain protein 1Zinc finger CW type with coiled coi