MOV10 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD86831A
Western blot analysis of extracts of various cell lines using MOV10 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using MOV10 Polyclonal Antibody at 1:1000 dilution.
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

Circle
Product Name
MOV10 Polyclonal Antibody
Catalog Number
RD86831A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs. Required for microRNA (miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC. Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1 in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7. Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity. May function as a messenger ribonucleoprotein (mRNP clearance factor. Exhibits antiviral activity against dengue virus (DENV.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human MOV10
Gene ID
4343
Swissprot
Q9HCE1
Synonyms
MOV10fSAP113gb110
Calculated MW
48kDa/93kDa/103kDa
Observed MW
105kDa

Applications

Circle
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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