This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human MSLN
Swissprot
Q13421
Synonyms
CAK 1CAK1CAK1 antigencleaved formMegakaryocyte potentiating factorMesothelinMesothelin isoform 1 precursorMPFMslnMSLNPre pro megakaryocyte potentiating factorPre-pro-megakaryocyte-potentiating factorSMRSMRPSoluble MPF mesothelin related prot
Gene Accession
BC009272
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4