MTHFD2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219239A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using MTHFD2 Polyclonal Antibody at dilution of 1:65(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using MTHFD2 Polyclonal Antibody at dilution of 1:65(×200)
Product Name
MTHFD2 Polyclonal Antibody
Catalog Number
RD219239A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
Immunogen Information
Immunogen
Fusion protein of human MTHFD2
Swissprot
P13995
Synonyms
Signal TransductionMetabolism
Gene Accession
BC001548
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
1.14 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.