MTOR Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70502A
Western Blot analysis of various samples using MTOR Polyclonal Antibody at dilution of 1:1000.
Product Name
MTOR Polyclonal Antibody
Catalog Number
RD70502A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. The antibody is specific to MTOR.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse mTOR
Swissprot
P42345,Q9JLN9,P42346
Synonyms
dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1)FK506 binding protein 12 rapamycin associated protein 1FK506 binding protein 12 rapamycin associated protein 2FK506 binding protein 12 rapamycin complex associated protein 1FK506-bindi
Calculated MW
289 kDa
Observed MW
289 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.