Mucin-5ACis aproteinthat in humans is encoded by theMUC5ACgene. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). Gel-forming glycoprotein of gastric and respiratoy tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microrganisms and particles that are subsequently removed by the mucocilary system. Highly expressed in surface mucosal cells of respiratory tract and stomach epithelia. Overexpressed in a number of carcinomas. Also expressed in Barrett's esophagus epithelium and in the proximal duodenum.
Immunogen Information
Immunogen
Synthetic peptide of human MUC5AC
Swissprot
P98088
Synonyms
ApomucinApomucin Major Airway GlycoproteinGastric mucinLeBLewis B blood group antigenMajor Airway GlycoproteinMUC 5MUC5MUC5ACMucin 5 subtype AC tracheobronchialMucin 5 Subtypes A And CMucin 5 subtypes A and C tracheobronchial/gastricMucin 5tr
Gene Accession
XP_003119529
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4