MutS Protein Homolog 2(MSH2) Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
Immunohistochemistry of paraffinembedded Human colon cancer tissue with MutS Protein Homolog 2(MSH2) Monoclonal Antibody(Antigen repaired by EDTA). Location: Nucleus.
Immunohistochemistry of paraffinembedded Human colon cancer tissue with MutS Protein Homolog 2(MSH2) Monoclonal Antibody(Antigen repaired by EDTA). Location: Nucleus.
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For more information on our kits, please contact us at info@reddotbiotech.com

Overview

Circle
Product Name
MutS Protein Homolog 2(MSH2) Monoclonal Antibody
Catalog Number
RD6750
Clonality
Monoclonal
Host
Mouse

Background

Circle
DNA mismatch repair (MMR) system is composed of enzyme molecules that specifically repair DNA base mismatch. The existence of this system can ensure the integrity and stability of genetic material, avoid the mutation of genetic material, and ensure the high fidelity of DNA replication. It is composed of hMLH1, hMSH2, hpms1, hPMS2 and other genes. HMSH2 is located in human chromosome 2p21-22, encoding a protein composed of 934 aa. The mutation of hMSH2 gene occurs in sporadic colorectal cancer. The mutation of microsatellite hMSH2 gene is related to 50% of familial and non-familial polyposis colorectal cancer (HNPCC).

Immunogen Information

Circle
Swissprot
P43246

Applications

Circle
Reactivity
Human
Tested Applications
Ready to use for IHC-P
Concentration
100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
Storage Buffer
TBS with 0.1% Proclin300, PH7.4

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