MUTYH Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of Hela cell using MUTYH Polyclonal Antibody at dilution of 1:500
Product Name
MUTYH Polyclonal Antibody
Catalog Number
RD77521A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human MUTYH
Swissprot
Q9UIF7
Synonyms
A/G specific adenine DNA glycosylaseA/G-specific adenine DNA glycosylaseAdenine DNA glycosylaseCYP2ChMYHMGC4416MutY (E. coli) homologMutY homolog (E. coli)MutY homologMutYE. colihomolog ofMutyhMUTYHMYHrMYH
Calculated MW
60 kDa
Gene Accession
BC003178
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas