This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.
Immunogen Information
Immunogen
Synthetic peptide of human MYCN
Swissprot
P04198
Synonyms
bHLHe37Class E basic helix-loop-helix protein 37MODEDmycnMYCNN mycN myc proto oncogene proteinN-myc proto-oncogene proteinNeuroblastoma derived v myc avian myelocytomatosis viral related oncogeneNeuroblastoma MYC oncogeneNMYCNMYC proto oncogene
Gene Accession
NP_005369
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4