MYSM1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78701A
Western Blot analysis of Mouse kidney tissue using MYSM1 Polyclonal Antibody at dilution of 1:1100
Immunohistochemistry of paraffin-embedded Human gastric cancer using MYSM1 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human cervical cancer using MYSM1 Polyclonal Antibody at dilution of 1:60
Product Name
MYSM1 Polyclonal Antibody
Catalog Number
RD78701A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
Immunogen Information
Immunogen
Synthetic peptide of human MYSM1
Swissprot
Q5VVJ2
Synonyms
2A-DUB2ADUBHistone H2A deubiquitinaseHistone H2A deubiquitinase MYSM1KIAA1915Myb like SWIRM and MPN domains 1Myb likeSWIRM and MPN domain containing proteinMyb likeSWIRM and MPN domains 1Myb-likeMyb-likeSWIRM and MPN domains 1MYSM 1mysm1MYS
Calculated MW
95 kDa
Gene Accession
NP_001078956
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas