MYSM1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76501A
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MYSM1 Polyclonal Antibody at dilution 1:50
Variation
Quantity
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Overview
Product Name
MYSM1 Polyclonal Antibody
Catalog Number
RD76501A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.Component of a large chromatin remodeling complex, at least composed of MYSM1, PCAF, RBM10 and KIF11/TRIP5. Binds histones
Immunogen Information
Immunogen
Synthetic peptide of human MYSM1
Swissprot
Q5VVJ2
Synonyms
2A-DUB2ADUBHistone H2A deubiquitinaseHistone H2A deubiquitinase MYSM1KIAA1915Myb like SWIRM and MPN domains 1Myb likeSWIRM and MPN domain containing proteinMyb likeSWIRM and MPN domains 1Myb-likeMyb-likeSWIRM and MPN domains 1MYSM 1mysm1MYS
Gene Accession
NP_001078956
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas