Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin),also known as CDH2 (cadherin 2),is a classical member of the cadherin superfamily which also include E-,P-,R-,and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons,endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis,synaptogenesis and synaptic plasticity .
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin
Swissprot
P19022,P15116,Q9Z1Y3
Synonyms
CADH2Cadherin 2Cadherin 2 N cadherin neuronalCadherin 2 type 1Cadherin 2 type 1 N cadherin neuronalCadherin 2type 1N-cadherin (neuronal)Cadherin-2Cadherin2Calcium dependent adhesion protein neuronalCD325CD325 antigenCDH2CDHNCDw325CDw325 an
Calculated MW
100/120/140 kDa
Observed MW
120 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:300-1:800
Concentration
200 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4