NBN Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD78593A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NBN Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NBN Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using NBN Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using NBN Polyclonal Antibody at dilution 1:50
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Overview

Circle
Product Name
NBN Polyclonal Antibody
Catalog Number
RD78593A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Immunogen Information

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Immunogen
Synthetic peptide of human NBN
Swissprot
O60934
Synonyms
AT V1AT V2ATVCell cycle regulatory protein p95FLJ10155MGC87362NbnNBNNBS 1NBSNBS1NibrinNijmegen breakage syndrome 1 (nibrin)Nijmegen breakage syndromeNijmegen breakage syndrome protein 1p95p95 protein of the MRE11/RAD50 complex
Gene Accession
NP_002476

Applications

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Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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