NBS1/NBN Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89414A
Western blot analysis of extracts of various cell lines using NBS1/NBS1/NBN Polyclonal Antibody at 1:1000 dilution.
Immunofluorescence analysis of U2OS cells using NBS1/NBS1/NBN Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Variation
Quantity
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Overview
Product Name
NBS1/NBN Polyclonal Antibody
Catalog Number
RD89414A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Immunogen Information
Immunogen
A synthetic peptide of human NBS1/NBN
Gene ID
4683
Swissprot
O60934
Synonyms
NBNAT-V1AT-V2ATVNBSNBS1P95nibrin
Calculated MW
15kDa/21kDa
Observed MW
Refer to figures
Applications
Reactivity
Human
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000,IF 1:50-1:200
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas