The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Immunogen Information
Immunogen
Recombinant protein of human NCK1
Swissprot
P16333
Synonyms
Cytoplasmic protein NCK1Melanoma Nck proteinMGC12668NCK 1NCK adaptor protein 1NCK alphaNCKNCK tyrosine kinaseNck-1NCK1NCK1NCKalphaNon catalytic region of tyrosine kinaseSH2/SH3 adaptor protein NCK alphaSH2/SH3 adaptor protein NCK-alpha
Calculated MW
43 kDa
Gene Accession
BC006403
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4