NCR2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78950A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NCR2 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using NCR2 Polyclonal Antibody at dilution 1:60
Product Name
NCR2 Polyclonal Antibody
Catalog Number
RD78950A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Natural cytotoxicity triggering receptor 2is aproteinthat in humans is encoded by theNCR2gene. NCR2 has also been designated asCD336(cluster of differentiation336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
Immunogen Information
Immunogen
Synthetic peptide of human NCR2
Swissprot
O95944
Synonyms
Activating NK receptor NKp44CD336CD336 antigendJ149M18.1LY95Lymphocyte antigen 95 (activating NK receptorNK p44)Lymphocyte antigen 95 homolog (activating NK receptorNK p44)Lymphocyte antigen 95 homologLymphocyte antigen 95mousehomolog ofNatur
Gene Accession
NP_001186438
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas