The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane.
Immunogen Information
Immunogen
Recombinant protein of human NDUFA1
Swissprot
O15239
Synonyms
CI MWFECI-MWFEComplex I MWFEcomplex I MWFE subunitComplex I-MWFEMWFEMWFEB. taurushomolog ofNADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDaNADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1NADH dehydrogenase [ubiquinone] 1 alpha su
Gene Accession
BC000266
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4