This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19.
Immunogen Information
Immunogen
Recombinant protein of human NDUFAF1
Swissprot
Q9Y375
Synonyms
CGI 65CGI65CIA30CIA30Complex I intermediate associated protein 30Complex I intermediate associated protein 30 mitochondrialComplex I intermediate-associated protein 30mitochondrialNADH dehydrogenase (ubiquinone) 1 alpha subcomplex assembly factor
Calculated MW
38 kDa
Gene Accession
BC000780
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4