This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions.
Immunogen Information
Immunogen
Recombinant protein of human NDUFS7
Swissprot
O75251
Synonyms
CI 20CI-20kDComplex I 20kDa subunitComplex I mitochondrial respiratory chain 20 KD subunitComplex I-20kDFLJ45860FLJ46880MGC120002MY017NADH coenzyme Q reductaseNADH dehydrogenase (ubiquinone) Fe S protein 7 20kDa (NADH coenzyme Q reductase)NADH
Gene Accession
BC005954
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4