NEDD4L Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76013A
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using NEDD4L Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NEDD4L Polyclonal Antibody at dilution 1:60
Product Name
NEDD4L Polyclonal Antibody
Catalog Number
RD76013A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension.
Immunogen Information
Immunogen
Recombinant protein of human NEDD4L
Swissprot
Q96PU5
Synonyms
E3 ubiquitin protein ligase NEDD4 like proteinE3 ubiquitin-protein ligase NEDD4-likeKIAA0439NED4LNEDD4 2NEDD4 2cNedd4-2NEDD4-2aNEDD4.2NEDD4bNEDD4LNEDD4LaNEDD4LbNEDD4LcNEDD4LdNEDD4LeNEDD4LfNEDD4LgNEDD4LhNEDL3Neural precursor cell expres
Gene Accession
BC032597
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas