The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human NEDD9
Swissprot
Q14511
Synonyms
Cas like dockingCas scaffolding protein family member 2CAS-LCAS2CasLCASLCASS2Crk associated substrate relatedCrk associated substrate related proteinCRK-associated substrate-related proteindJ49G10.2 (Enhancer of Filamentation 1 (HEF1))dJ49G10.2
Calculated MW
93 kDa
Gene Accession
BC020686
Applications
Reactivity
Human
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4