NFATC2IP Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD88493A
Western blot analysis of extracts of various cell lines using NFATC2IP Polyclonal Antibody at 1:1000 dilution.
Variation
Quantity
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Overview
Product Name
NFATC2IP Polyclonal Antibody
Catalog Number
RD88493A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
In T-helper 2 (Th2 cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity.
Immunogen Information
Immunogen
Recombinant fusion protein of human NFATC2IP
Gene ID
84901
Swissprot
Q8NCF5
Synonyms
NFATC2IPESC2NIP45RAD60
Calculated MW
65kDa
Observed MW
68kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.