The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse IKBβ
Swissprot
Q15653,Q60778,Q9JIA3
Synonyms
I kappa B betaI-kappa-B-betaIkappaBbetaIKB betaIkB-BIkB-betaIKBBIKBBIkBbetaNF kappa BIBNF-kappa-B inhibitor betaNF-kappa-BIBNfkbibThyroid receptor interacting protein 9Thyroid receptor-interacting protein 9TR interacting protein 9TR-intera
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:300
Concentration
0.66 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4