Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Immunogen Information
Immunogen
Synthetic peptide of human NIT2
Swissprot
Q9NQR4
Synonyms
CUA002MGC111199NIT 2Nit protein 2NIT2NIT2Nitrilase family member 2Nitrilase homolog 2Omega amidase NIT2Omega-amidase NIT2
Calculated MW
31 kDa
Gene Accession
NP_064587
Applications
Reactivity
Human,Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:1000-1:5000, IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4