NLRP4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD79164A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NLRP4 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using NLRP4 Polyclonal Antibody at dilution 1:30
Product Name
NLRP4 Polyclonal Antibody
Catalog Number
RD79164A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes
Immunogen Information
Immunogen
Synthetic peptide of human NLRP4
Swissprot
Q96MN2
Synonyms
Cancer/testis antigen 58CLR19.5CT58FLJ32126NACHTleucine rich repeat and PYD containing 4NACHTLRR and PYD containing protein 4NACHTLRR and PYD domains-containing protein 4NALP4NLR familypyrin domain containing 4NLRP4Nucleotide binding oligome
Gene Accession
NP_604393
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas