NLRP6 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76979A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NLRP6 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human brain tissue using NLRP6 Polyclonal Antibody at dilution 1:50
Variation
Quantity
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Overview
Product Name
NLRP6 Polyclonal Antibody
Catalog Number
RD76979A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human NLRP6
Swissprot
P59044
Synonyms
Angiotensin II/vasopressin receptorAVRCLR11.4NACHTleucine rich repeat and PYD containing 6NACHTLRR and PYD containing protein 6NACHTLRR and PYD domains-containing protein 6NAVRNAVR/AVRNLR familypyrin domain containing 6Nlrp6NLRP6Nucleotide
Gene Accession
NP_612202
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas