Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
Immunogen Information
Immunogen
Recombinant protein of human NME6
Swissprot
O75414
Synonyms
Inhibitor of p53 induced apoptosis alphaInhibitor of p53-induced apoptosis-alphaIPIA ALPHAIPIA-alphaNDK 6NDK6NDP kinase 6NM23 H6nm23-H6NM23H6Nme6Nucleoside diphosphate kinase 6OTTHUMP00000164810OTTHUMP00000210736OTTHUMP00000210737OTTHUMP000
Calculated MW
21 kDa
Gene Accession
BC001808
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4