NOD2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76743A
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using NOD2 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using NOD2 Polyclonal Antibody at dilution 1:40
Product Name
NOD2 Polyclonal Antibody
Catalog Number
RD76743A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.
Immunogen Information
Immunogen
Synthetic peptide of human NOD2
Swissprot
Q9HC29
Synonyms
ACUGArthrocutaneouveal granulomatosisBLAUCARD15Caspase recruitment domain familymember 15Caspase recruitment domain protein 15Caspase recruitment domain-containing protein 15CDCLR16.3IBD1Inflammatory bowel disease protein 1LRR containing prote
Gene Accession
NP_071445
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas