NOX4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70417A
Western Blot analysis of various samples using NOX4 Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry analysis of parafffin-embedded human kidney using NOX4 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry analysis of parafffin-embedded mouse kidney using NOX4 Polyclonal Antibody at dilution of 1:400.
Product Name
NOX4 Polyclonal Antibody
Catalog Number
RD70417A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse NOX4
Swissprot
Q9NPH5,Q9JHI8,Q924V1
Synonyms
Kidney oxidase 1Kidney oxidase-1Kidney superoxide producing NADPH oxidaseKidney superoxide-producing NADPH oxidaseKOX 1KOXKox-1KOX1NADPHNADPH oxidase 4Nox4NOX4Renal NAD(P)H oxidaseRenal NAD(P)H-oxidaseRENOX
Calculated MW
70 kDa
Observed MW
70 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:1000-1:2000, IHC 1:400-1:1000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.