This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.
Immunogen Information
Immunogen
Recombinant protein of human NR1D1
Swissprot
P20393
Synonyms
EAR-1EAR1ERBA-related 1hRevNr1d1NR1D1Nuclear receptor Rev ErbA alphaNuclear receptor subfamily 1 group D member 1Rev erbAalphaRev erbalphaRev-erbA-alphaRev-ErbAalphaReverbaTHRA1THRALThyroid hormone receptoralpha likeThyroid hormone recept
Gene Accession
BC047875
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4