NTRK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266502A
Western blot analysis of extracts of various cell lines using NTRK1 Polyclonal Antibody at dilution of 1:500.
Immunohistochemistry of paraffin-embedded Rat liver using NTRK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human stomach using NTRK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using NTRK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
NTRK1 Polyclonal Antibody
Catalog Number
RD266502A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Immunogen Information
Immunogen
A synthetic peptide of human NTRK1 (NP_002520.2).
Gene ID
4914
Swissprot
P04629
Synonyms
NTRK1MTCTRKTRK1TRKATrk-Ap140-TrkA
Calculated MW
77 kDa/83 kDa/86 kDa/87 kDa
Observed MW
140 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas