This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse Neurotensin
Swissprot
P30990,Q9D3P9
Synonyms
Human proneurotensinLarge neuromedin NNeuromedin N preproproteinNeurotensin/neuromedin NNEUTNMN 125NmNNmN-125NNNTNT/NNTRHNTSNTS1Pro neurotensin/neuromedinProneuromedin N mRNATail peptide
Calculated MW
20 kDa
Observed MW
20 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:300-1:800
Concentration
0.54 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4