OGDH Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80950A
Immunohistochemistry of paraffin-embedded Rat brain using OGDH Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using OGDH Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using OGDH Polyclonal Antibody
Product Name
OGDH Polyclonal Antibody
Catalog Number
RD80950A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Immunogen Information
Immunogen
Recombinant fusion protein of human OGDH (NP_001003941.1).
Gene ID
4967
Swissprot
Q02218
Synonyms
OGDHAKGDHE1kOGDC
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,IF
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas