This gene encodes a member of the Cut homeobox family of transcription factors. Expression of the encoded protein is enriched in the liver, where it stimulates transcription of liver-expressed genes, and antagonizes glucocorticoid-stimulated gene transcription. This gene may influence a variety of cellular processes including glucose metabolism, cell cycle regulation, and it may also be associated with cancer. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Synthetic peptide of human ONECUT1
Swissprot
Q9UBC0
Synonyms
hepatocyte nuclear factor 6 alphaHepatocyte nuclear factor 6HNF 6HNF-6HNF6HNF6AOne cut domain family member 1One cut homeobox 1Onecut1