OPTC Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266838A
Western blot analysis of extracts of various cell lines using OPTC Polyclonal Antibody at dilution of 1:1000.
Product Name
OPTC Polyclonal Antibody
Catalog Number
RD266838A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).
Immunogen Information
Immunogen
Recombinant fusion protein of human OPTC (NP_055174.1).
Gene ID
26254
Swissprot
Q9UBM4
Synonyms
OPTCOPTopticin
Calculated MW
37 kDa
Observed MW
54 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.