OTC Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western Blot analysis of Mouse liver tissue using OTC Polyclonal Antibody at dilution of 1:800
Immunohistochemistry of paraffin-embedded Human tonsil using OTC Polyclonal Antibody at dilution of 1:50
Product Name
OTC Polyclonal Antibody
Catalog Number
RD76031A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
Immunogen Information
Immunogen
Recombinant protein of human OTC
Swissprot
P00480
Synonyms
EC 2.1.3.3MGC129967MGC129968MGC138856OCTDOrnithine carbamoyltransferase mitochondrialOrnithine carbamoyltransferasemitochondrialOrnithine transcarbamylaseOtcOTCOTCase
Calculated MW
40 kDa
Gene Accession
BC107154
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas