The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse P2X3
Swissprot
Q3UR32,P49654
Synonyms
ATP receptorMGC129956P2rx3P2RX3P2X purinoceptor 3P2X receptor subunit 3P2X3Purinergic receptorPurinergic receptor P2X ligand gated ion channel 3Purinergic receptor P2X3Purinoceptor P2X3
Applications
Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:500-1:2000
Concentration
420 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4