P2RX3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77013A
Western Blot analysis of Human bladder and bladder transitional cell carcinoma tissue using P2RX3 Polyclonal Antibody at dilution of 1:250
Immunohistochemistry of paraffin-embedded Human thyroid cancer using P2RX3 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human prostate cancer using P2RX3 Polyclonal Antibody at dilution of 1:50
Product Name
P2RX3 Polyclonal Antibody
Catalog Number
RD77013A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
Immunogen Information
Immunogen
Synthetic peptide of human P2RX3
Swissprot
P56373
Synonyms
ATP receptorMGC129956P2rx3P2RX3P2X purinoceptor 3P2X receptor subunit 3P2X3Purinergic receptorPurinergic receptor P2X ligand gated ion channel 3Purinergic receptor P2X3Purinoceptor P2X3
Calculated MW
44 kDa
Gene Accession
NP_002550
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:25-1:100
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas