The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.
Immunogen Information
Immunogen
Synthetic peptide of human P2RY1
Swissprot
P47900
Synonyms
ATP receptorP2 purinoceptor subtype Y1P2RY1P2RY1P2Y purinoceptor 1P2Y1P2Y1 purinoceptorPlatelet ADP receptorPurinergic receptorPurinergic receptor P2Y G protein coupled 1Purinergic receptor P2Y1
Gene Accession
NP_002554
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4