p63 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD70481A
Western Blot analysis of various samples using p63 Polyclonal Antibody at dilution of 1:1000.
Variation
Quantity
For more information on our kits, please contact us at info@reddotbiotech.com
Overview
Product Name
p63 Polyclonal Antibody
Catalog Number
RD70481A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.
Immunogen Information
Immunogen
Recombinant protein corresponding to Mouse P63
Swissprot
Q9H3D4,O88898,Q9JJP6
Synonyms
AISAmplified in squamous cell carcinomaB(p51A)B(p51B)Chronic ulcerative stomatitis proteinCUSPDN p63 alpha 1DNp63EEC3id:ibd3516Keratinocyte transcription factorKeratinocyte transcription factor KETKETLMSMGC115972MGC192897NBPOFC8OTTHUMP00
Calculated MW
50-75 kDa
Observed MW
75 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
330 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas