This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
Immunogen Information
Immunogen
Recombinant protein of human PABPC1
Swissprot
P11940
Synonyms
PAB 1PAB1PABP 1PABP1PABPC 1PABPC1PABPC2PABPL1Poly A binding protein 1Poly A binding protein cytoplasmic 1poly(A) binding proteincytoplasmic 1poly(A) binding proteincytoplasmic 2Polyadenylate binding protein 1
Calculated MW
71 kDa
Gene Accession
BC015958
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4