PACS1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87496A
Western blot analysis of extracts of 293T cells using PACS1 Polyclonal Antibody at 1:3000 dilution.
Variation
Quantity
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Overview
Product Name
PACS1 Polyclonal Antibody
Catalog Number
RD87496A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Immunogen Information
Immunogen
Recombinant fusion protein of human PACS1
Gene ID
55690
Swissprot
Q6VY07
Synonyms
PACS1MRD17SHMS
Calculated MW
121kDa/127kDa
Observed MW
128kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:1000-1:3000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.