PADI4 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD252164A
Western blot analysis of 293T cell lysates  using PADI4 Polyclonal Antibody at dilution of 1:400
Western blot analysis of 293T cell lysates using PADI4 Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human tonsil tissue  using PADI4 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using PADI4 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue  using PADI4 Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PADI4 Polyclonal Antibody at dilution of 1:35(×200)
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Overview

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Product Name
PADI4 Polyclonal Antibody
Catalog Number
RD252164A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.

Immunogen Information

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Immunogen
Fusion protein of human PADI4
Swissprot
Q9UM07
Synonyms
EC 3.5.3.15HL 60 PADHL-60 PADPAD 4PADPADI 4PADI 5PADI H proteinPadi4PADI4PADI5PDI 4PDI 5PDI4PDI5Peptidyl arginine deiminase type IVPeptidyl arginine deiminase type VPeptidylarginine deiminase IVProtein arginine deiminaseProtein arginine
Calculated MW
74 kDa
Observed MW
Refer to figures
Gene Accession
BC025718

Applications

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Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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