PAI1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD86693A
Western Blot analysis of Rat placenta using PAI1 Polyclonal antibody at dilution of 1:1000.
Western Blot analysis of Rat placenta using PAI1 Polyclonal antibody at dilution of 1:1000.
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Overview

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Product Name
PAI1 Polyclonal Antibody
Catalog Number
RD86693A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.

Immunogen Information

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Immunogen
Recombinant Rat PAI1 protein expressed by Mammalian
Swissprot
P20961
Synonyms
Plasminogen activator inhibitor 1PAI-1Endothelial plasminogen activator inhibitorSerpin E1SERPINE1PLANH1
Calculated MW
26kDa
Observed MW
28kDa

Applications

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Reactivity
Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:250-1:500
Concentration
4.3mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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