PAK6 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77549A
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PAK6 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PAK6 Polyclonal Antibody at dilution 1:40
Product Name
PAK6 Polyclonal Antibody
Catalog Number
RD77549A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant protein of human PAK6
Swissprot
Q9NQU5
Synonyms
CDKN1A activated kinase 6EC 2.7.1.37p21 activated protein kinase 6p21 protein (Cdc42/Rac)-activated kinase 6p21(CDKN1A) activated kinase 6p21-activated kinase 6p21activated kinase 6PAK 5PAK 6PAK-5PAK-6PAK5Pak6PAK6Serine threonine protein kin
Gene Accession
BC035596
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:100
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas