PAM16 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD253027A
Western blot analysis of HepG2 and Jurkat cell lysates  using PAM16 Polyclonal Antibody at dilution of 1:700
Western blot analysis of HepG2 and Jurkat cell lysates using PAM16 Polyclonal Antibody at dilution of 1:700
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using PAM16 Polyclonal Antibody at dilution of 1:50(×200)
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PAM16 Polyclonal Antibody at dilution of 1:50(×200)
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Overview

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Product Name
PAM16 Polyclonal Antibody
Catalog Number
RD253027A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities.

Immunogen Information

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Immunogen
Fusion protein of human PAM16
Swissprot
Q9Y3D7
Synonyms
CGI-136MAGMASMagmas like proteinMitochondria associated protein involved in granulocyte macrophage colony stimulating factor signal transductionMitochondria-associated granulocyte macrophage CSF-signaling moleculeMitochondrial import inner membrane t
Calculated MW
14 kDa
Observed MW
Refer to figures
Gene Accession
BC005024

Applications

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Reactivity
Human, Mouse
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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