This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.
Immunogen Information
Immunogen
Synthetic peptide of human PAPPA
Swissprot
Q13219
Synonyms
ASBABP2Aspecific BCL2 ARE binding protein 2Differentially placenta 1 expressed proteinDIPLA1EC 3.4.24.79IGF dependent IGFBP 4 proteaseIGF-dependent IGFBP-4 proteaseIGFBP 4aseIGFBP-4aseIGFBP4aseInsulin like growth factor dependent IGF binding pro
Gene Accession
NP_002572
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4