This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.PARD3 (Par-3 Family Cell Polarity Regulator) is a Protein Coding gene. Diseases associated with PARD3 include Gamma Heavy Chain Disease and Enamel Caries. Among its related pathways are Transcriptional activity of SMAD2/SMAD3-SMAD4 heterotrimer and Ras signaling pathway. GO annotations related to this gene include protein phosphatase binding and phosphatidylinositol-4,5-bisphosphate binding. An important paralog of this gene is PARD3B.
Immunogen Information
Immunogen
Recombinant Rat Partitioning defective 3 homolog protein
Swissprot
Q9Z340
Synonyms
agouti signaling proteinASIPAtypical PKC isotype specific interacting proteinAtypical PKC isotype-specific-interacting proteinBazbazookaCoagulation factor II receptor-like 2CTCL tumor antigen se2-5F2rl2PAR-3par-3 family cell polarity regulator a
Calculated MW
151 kDa
Observed MW
151 kDa
Applications
Reactivity
Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
2 mg/mL
Storage Buffer
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.